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In a doubleblind, placebocontrolled study, 22 participants applied a formula containing 0.1% Ginkgo biloba extract and 0.5% carboxymethyl1,3glucan twice daily on one forearm, with the other side receiving placebo, for 2 weeks

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[DOI] [PMC free article] [PubMed] [Google Scholar] [12].Landmesser U, Dikalov S, Price SR, McCann L, Fukai T, Holland SM, Mitch WE, Harrison DG, Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension