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The nanoplatform CS@KET/P780NPs induces apoptosis by enhancing ROS accumulation, which triggers ICD and a long-term antitumor response by releasing tumor-associated antigens (TAA) and DAMPs (245)

Eur J Nucl Med Mol Imaging 39:17671777

however, its utilization significantly declined following findings from the Heart and Estrogen/Progestin Replacement Study (HERS) (161)and the Womens Health Initiative (WHI) (162, 163) randomized trials

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