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We demonstrated that the expression of key enzymes involved in FA metabolism were substantially reduced in the kidneys of cKOt mice, particularly enzymes involved in FA uptake (CD36 and FATP2), shuttling of acylcarnitines into the mitochondria (CPT1, CPT2, CRAT, and CACT), and catalysis of the initial step of -oxidation (ACADS, ACADM, ACADL, and ACADVL)

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