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At present, it is widely accepted that GSH acts not only as a reducing agent and a major antioxidant within the cells, but also as a mediator of many other physiologic reactions including metabolism of xenobiotics, thiol disulfide exchange reactions, and cellular signaling (cell-cycle regulation, proliferation, and apoptosis)

For cell samples that were not immediately processed, they were stored at 80 C

[DOI] [PubMed] 98.Cusick SE, Georgieff MK

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Glutamate signaling dysfunction and dysregulation of oxidative stress have been considered to play essential roles in schizophrenic prodrome [22]