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Some properties of glutathione biosynthesis-deficient mutants of Escherichia coli B

Understanding how these pathways intersect and influence each other will inform the rational design of combination therapies that exploit their complementary mechanisms

Nevertheless, more clinical research is necessary to fully understand its impact (135)

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ATF2 could integrate environmental cues (such as GSH levels) to regulate gene expression programs [57], and had participated in cell proliferation, survival, and metastasis in various tumors by regulating target genes [58,59,60]