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The ketogenic diet does require RGCs to utilize ketone bodies for fuel, which obligates mitochondrial respiration and the attendant ROS generation that oxidative phosphorylation entails

Evaluation of vitamin B12 effects on DNA damage induced by pioglitazone

Ferroptosis inducers, including erastin and RSL3, have shown efficacy in NSCLC models, especially against resistance to EGFR inhibitors

doi: 10.3390/horticulturae8050356 30

Thus, SIRT1 may act as a bridge connecting the circadian clock, autophagy, redox state, and inflammation
