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STK11/LKB1 inactivating mutations often cooccur with KRAS-activating mutations, and STK11/LKB1 inactivating mutations are also a driver of primary resistance to immunotherapy in KRAS-mutant lung adenocarcinoma (LUAD) (Qian et al., 2023)

However, problems begin to occur when the number of free radicals exceeds what our bodies can process naturally, resulting in an increased presence of free radicals that can damage cells and compromise bodily functions

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Other 1 H MRS detectable muscle metabolites also did not differ significantly between the groups

However, this hypothesis needs further and more detailed investigation