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and (4) studies published in English from inception to June 2024

The kidney plays an important role in carnitine recycling by reducing the loss of carnitine through its reabsorption and ensuring the effective utilization of carnitine

Carnitine, Acylcarnitines and Fatty Acid Transport into Mitochondria The substrates for oxidation and most of the energy production in cells are unesterified fatty acids, which originate from three main sources: exogenous fatty acids that enter cells from the circulation, either from the diet or by mobilization from other tissues, those that arise via synthesis de novo from acetyl-CoA, and those released within the cell by the hydrolysis of phospholipids and triacylglycerols

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