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54 Physiological Factors Graying hair becomes more visible with age as melanin production in hair follicles declines

This paradoxical clinical application warrants closer scrutiny and further investigation

Nicholson LB (2016) The immune system

If homeostatic control does not maintain the concentrations of zinc and other essential metal ions in a physiological range, a phenomenon referred to as dyshomeostasis, mismetalation of a metalloprotein with the wrong metal ion can occur
thus, the mitochondrial pool is supplied by GSH transport and maintained by reducing its oxidized form via the activity of glutathione reductase
