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[PubMed 8470693] 1629

But there are still the unknowns we havent decided about

At 24 h, no regulation was observed in HepG2 cells, but HepG2 ATP7B-KO cells showed a dose-dependent reduction, with 0.6mmol/l CuCl reducing promoter activity by 50.76%

5 The nervous system development-related factor L1 cell adhesion molecule (L1CAM), which is expressed in neurons and tumour cells, has been proven to facilitate the spread of BCBM cells to the parenchymal side of capillaries and eventually to establish metastatic outgrowth by activating downstream neuroserpin, which prevents the production of brain-metastasis-suppressing plasmin by astrocytes (see later)

Mercadante et al., 2019