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Cole AM, Liao HI, Stuchlik O, Tilan J, Pohl J, Ganz T: Cationic polypeptides are required for antibacterial activity of human airway fluid

That last clause is the whole game

2018;27(3):667-676.e4
10.1074/jbc.M213032200

It is not usually used as a first-line therapy, but in selected patients, it may help strengthen disease control as part of the main treatment plan
