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3 Challenges in diagnosis and treatment of neurodegenerative diseases 3.1 Diagnostic odyssey The diagnostic odyssey for rare neurodegenerative disorders is a lengthy and unpredictable process
Science 277:16591662
The significance of ApoE4 is such that ApoE4 +/+ carriers could represent a distinct genetic AD variant based on very high penetrance (Fortea et al., 2024)
Others do not
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