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[63] showed that sertraline reduced the viability of AU565 (HER2positive breast cancer) cells by downregulating cyclin D1 and upregulating CDK inhibitors p21 and p27, resulting in G1/S cell cycle arrest and caspase3mediated apoptosis

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C/EBP homologous protein-10 (CHOP-10) limits postnatal neovascularization through control of endothelial nitric oxide synthase gene expression