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There are numerous delivery forms for glutathione including intravenous, nasal spray, liposomal, transdermal and oral dosage forms including tablets, capsules, powders, and sprays

For each iteration, we regenerated a new model based on the gene expression and a partial set of the metabolite uptake and secretion rates and used these models to predict the flux rate through the reaction whose flux measurement was omitted

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The on-bench and in vitro experimental studies demonstrate that the characteristic hypercarbon-tetragold(I) multi-center bonding in PAA4 and PAA5 not only guarantees their stability under common physiological conditions, but also facilitates a glutathione (GSH)-triggered prompt and synergetic release of active Au(I) ions in the GSH-overexpressed and acidic microenvironment of human bladder cancer EJ cells

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