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Cancer risk in people with a cancer history, because of NNMT's complex role in tumor biology

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This age group comprises 11% of the population age 65 and older in 2026 and is expected to comprise 21% of the population age 65 and older in 2060

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At the ultrastructural level, irregular and immature elastin fibers and fibers devoid of microfibrils were observed. These findings suggested that both elastic fiber abnormalities and reduced collagen content contribute to the clinical features seen in patients with clEDS. There were no consistent electron microscopy (EM) findings in the ten patients in our cohort who had EM performed