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Using a controlled cortical impact model of TBI, we used post-natal day (PND) 21 rat pups and acquired longitudinal 1H-MRS of the ipsilateral perilesional and contralateral hippocampi 24 h, 24 h, 72 h, 7 days, and 21 days post injury

All the murine models were then presented with a fibrin sealing agent, where some murine models were also presented with thymosin beta 4 (TB-500)

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Designed for controlled research environments