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Standard reconstitution: Add 3.0ml bacteriostatic water to a 20mg vial Resulting concentration: approximately 6.67mg/ml (6670mcg/ml) For 100mcg dose: draw approximately 0.015ml (1.5 units on U-100 insulin syringe) For 200mcg dose: draw approximately 0.03ml (3 units) The small volumes involved with Testagen dosing make accurate measurement challenging

Famotidine was associated with 2-hydroxypropyl--cyclodextrin to form an inclusion complex in order to decrease the degradation rate of the drug under acidic conditions [30]

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Acknowledgements The authors thank Netta Ussyshkin for critical reading of the paper