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This hypothesis remains to be tested empirically

While nanomaterials can help reduce H 2 gas leakage and assist in targeted H 2 therapy, their longterm safety, potential for abnormal immune responses, and biodegradability still require further validation in preclinical and clinical trials

One cluster analysis of 131 ME/CFS patients diagnosed according to the Fukuda criteria revealed that 34% of patients experienced sympathetic symptoms with dysautonomia (and were associated with more severe disease severity), 5% from sympathetic symptoms alone, 21% parasympathetic, and 40% struggled with sympathovagal balance (331)

105 LouandreC.EzzoukhryZ.GodinC.BarbareJ

In fact, the direct antimicrobial activities of the proteinase inhibitors were not determined to date, but it is possible that the inhibitors could interfere with acyl-serine proteases involved in bacterial cell wall synthesis