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To assess drug release, we applied FITC-conjugated D-CuP hydrogel to the wounds and measured the fluorescence signal of the residual hydrogel at predetermined time intervals in darkness

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Furthermore, the elucidation of the viral entry mechanism through mGluR2, due also to its predominant expression in brain tissues, unlike the recognised internalising receptor ACE2, may provide insights into the severe impact of COVID-19 on the brain and its intricate relationship with astrocyte damage, aberrant neuroinflammation, excitotoxicity, impairment of the glymphatic system as well as DLPFC and hippocampal injury [18, 233, 239]