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Description
The causes of deficiency range from chronic gastrointestinal disease to hereditary disease, but what is clear is the health impact of low levels

Breeding severely vitamin B12-deficient mice as model animals

The gap between the gene expression research (which suggests systemic biological effects) and the actual human evidence (which is limited to topical skin endpoints) is substantial
The impact on the gallbladder is much less

Crucial for adaptive immunity (targeting a specific pathogen)
