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2 Adaptive Immunity and Vaccine Effectiveness Adaptive immunity is particularly pertinent to vaccine effectiveness, since studies demonstrate a correlation between lack of sleep, a weakened immune response and subsequent reduction in vaccine protectiveness

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As it has been established previously that PABA apart from being used as a precursor of folate molecules, can protect the intracellular environment of the bacterial cells against free radicals, including reactive oxygen species (ROS) and reactive nitrogen species (RNS) by directly interacting with radicals of hydroxyl ions which prevent deoxyribose oxidation 47,79

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