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It was found that the use of inhibitors of ferroptosis could reduce cigarette smoke-induced cell death, suggesting that ferroptosis plays an important role in cigarette smoke-induced trophoblast cell death and may contribute to miscarriage ( 5 Pathophysiological mechanism 5.1 Molecular mechanisms of ferroptosis Ferroptosis is a regulated form of cell death characterized by iron-dependent lipid peroxidation and oxidative stress, playing a significant role in RM through trophoblast dysfunction

doi: 10.1016/s0891-5849(96)00271-7

Yes, but only under the right circumstances

According to toxicological studies, curcumin does not cause any discernible mutagenic, teratogenic, or subchronic toxicity damage

Curcumin as a promising therapy for COVID-19: A review