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This has led to the formulation of hypotheses such as the efficiency tradeoff hypothesis, which posits that the brain prioritizes the speed of ATP production via glycolysis over its efficiency during activation (Theriault et al., 2023)

[DOI] [PMC free article] [PubMed] [Google Scholar] 197.Martnez Steele E., Khandpur N., da Costa Louzada M.L., Monteiro C.A
This review provides in-depth details of the molecular mechanisms by which paracellular permeability is regulated, with relevance to disease conditions of the gastrointestinal tract

But if flare-ups start soon after adding a resurfacing serum, thats a strong indicator
