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IGF1R is linked to various cytoplasmic second messenger molecules including the RAS-MAPK and PI3K signaling networks
This shift provides information about the local environments polarity, dynamics, and rigidity, making it useful for monitoring protein stability, conformational changes, and ligand binding
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10.1038/nature20413 181 TortelliR.ZeccaC.PiccininniM.BenmahamedS.DellAbateM
