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As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Tilg et al., 2020)

This absence of hyperglycemic effects makes the peptide safer for individuals concerned about glucose metabolism, and the lack of IGF-1 elevation reduces theoretical concerns about cell proliferation

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Biochemical pharmacology

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