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Handling must only be performed by qualified and trained laboratory professionals in accordance with applicable regulations and institutional guidelines

The published mouse work that showed fat-loss effects delivered the compound by injection, at roughly 20 mg per kilogram per day, which does not convert cleanly to a human capsule

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Weight gain is caused by a combination of factors

In contrast to findings with behavioral 20,21,22 and other pharmacological interventions 10,12,13 , the similar mean weight loss achieved with semaglutide 2.4 mg in STEP 5 at weeks 52 and 104 (15.6% and 15.2%, respectively) suggests that, on average, there is minimal weight regain over 104 weeks when once-weekly semaglutide therapy is continued