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To counteract these oxidants, cells have developed antioxidant systems, including antioxidant enzymes, for example, superoxide dismutases (SOD13), catalase, glutathione peroxidases (GPx18), thioredoxins (Trx12), and peroxiredoxins (Prx16)

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They sit within a broader wave of emerging peptide trends that researchers and clinicians are still trying to place on the spectrum between experimental biology and mainstream medicine

In our opinion, even though all in vitro and in vivo studies provide useful information and hints for clinical trials with melatonin and DPP-4i or its combinational use, extensive work in clinical studies is still essential, and it may be possible to employ multi-functional drugs with a different mechanism of action to fight these multifactorial complications in DM of DNP and neuropathic pain

Improving Salinity Tolerance in Salvia officinalis L