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doi: 10.1097/00003246-199206000-00029 18 BooneB

In gastrointestinal lesions (indomethacin (30 mg/kg s.c.), aspirin (400 mg/kg i.g.) and diclofenac (125 mg/kg i.p.)) studies, NaBPC157 (10 g or 10 ng/kg i.p.) was given regularly, either simultaneously and/or one hour prior to drug application (indomethacin)

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The FIDELITY analysis (2024) of the FIDELIO-DKD and FIGARO-DKD trials reported a 19% reduction in combined kidney and cardiovascular outcomes in T2DM patients, with a lower incidence of DR progression in the finerenone group compared to placebo (142)