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In vivo role of catalase-peroxidase in synechocystis sp

Numerous in vivo and in vitro experiments have demonstrated that melatonin treatment has a significant effect on alleviating liver fibrosis (120).As the key effector cells in the process of liver fibrosis, HSCs can be activated under conditions of inflammation and oxidative stress, leading to excessive proliferation and transdifferentiation into myofibroblasts

Free radicals are generated from regulated and unregulated sources (e.g., mitochondrial respiration, enzymatic activities, electron leakage), and their responsiveness to environmental and nutritional stressor events overwhelms the antioxidant defenses in the body maintain redox homeostasis, thus leading to oxidative distress

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Systematic review with network meta-analysis: the comparative effectiveness and safety of interventions in patients with overt hepatic encephalopathy
