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Description
Its primary target organ appears to be the skeletal muscle, and its cellular actions inhibit the folate cycle and its tethered de novo purine biosynthesis, leading to AMPK activation
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Rohatgi PR, Swisher SG , Correa AM, Wu TT, Liao Z, Komaki R, Walsh G, Vaporciyan A, Lynch PM, Rice DC, Roth JA, Ajani JA
Specifically, we found that PANC-1 cells had relatively higher levels of GSTM3 expression, whereas MIA PaCa-2 cells had relatively lower levels (Figure 2A)
Similar findings were also shown by Okada et al
