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The verification of the purity of the N-Hcy-Lys peak was performed using the Peak purity test which is available in the HPLC software (HP ChemStation software, Rev

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Impaired FAD-dependent enzyme activity is also detrimental to bloodbrain barrier (BBB) integrity, leading to downregulation of tight-junction proteins such as claudin-5 and occluding, increased permeability, and enhanced peripheral immune infiltration