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Oral dosing keeps plasma ascorbate below roughly 220 micromoles per liter (mol/L), whereas controlled IV infusion can safely **generate** pharmacologic concentrations of 2530 millimoles per liter (mmol/L)a finding documented by Mark Levines National Institutes of Health group in Vitamin C pharmacokinetics: implications for oral and intravenous use (Padayatty and colleagues, Annals of Internal Medicine, 2004)

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Consider these signs: Dark patches that gradually appear, especially on cheeks, forehead, or hands Unusually dry or flaky skin that doesnt respond to moisturisers Fatigue or brain fog accompanying skin issuesthese might hint at B12 or Iron deficiencies Skin that bruises easily or looks dull and lifeless despite exfoliating routines Ignoring such indicators lets the cycle continue

Safety of Combining NAD+ and AOD9604 When considering "NAD+ and AOD9604 which should one take and what about combining," the safety of the combination is currently not extensively studied