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However, these therapies only partially decrease antibody levels and complement activity and require extended courses of treatment (5 days for intravenous immunoglobulin and 714 days for plasma exchange), limiting their effectiveness in addressing acute neuronal damage during the active phase of disease

Deerfield, IL: Baxter Healthcare Corp

2022 Jun 16;23(12):6699

Setmelanotide (Imcivree) Setmelanotide is an 8-mer cyclic peptide amide with the sequence Ac-RCaHfRWC-NH 2

Others say brief room temperature exposure followed by prompt refrigeration is acceptable as long as you account for the cumulative time out of the fridge