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10.1016/j.lfs.2016.05.026 Summary Keywords atrial fibrillation, obesity, fatty acids oxidation, lipotoxicity, l-carnitine, AMPK (5-AMP activated kinase) Citation Zhang Y, Fu Y, Jiang T, Liu B, Sun H, Zhang Y, Fan B, Li X, Qin X and Zheng Q (2021) Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity
Interestingly, the activity and toxicity of the numerous VPA metabolites are poorly understood
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Indeed, VPA-treated patients may be carnitine depleted despite having normal carnitine serum levels [49]
