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For instance, berberines ability to modulate Lactobacillus , Bacteroides , and Clostridium species has been elucidated using metagenomic sequencing

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The underlying biochemistry implicates low GSH as an important contributing factor in the development of several chronic illnesses that have been associated with increased oxidative stress such as metabolic syndrome, kidney disease, neurodegenerative diseases, liver disease, and cardiovascular diseases

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