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22: 31529 Gaberc-Porekar V, Zore I, Podobnik B, et al
It was first isolated from human plasma in 1973 by Dr

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Signaling pathways from Trk activation: PI3K/Akt pathway phosphorylates Bad (pro-apoptotic protein) preventing it from blocking Bcl-2 and Bcl-xL (anti-apoptotic proteins)
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