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Description
The main outcome variable to be monitored in both treatment arms is the normalisation of the serum vitamin B12 concentration at weeks 8, 26 and 52
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AhR signaling downregulates the expression of MLCK, which results in the dephosphorylation (and subsequent activation) of non-muscle myosin II-A and ezrin under inflammatory conditions

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Summary Novo Nordisk will report the topline results from the REDEFINE-1 trial of CagriSema in obese patients before the end of the year
