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Therefore, a thorough medical history may be helpful for differential diagnosis, but the differentiation of physiological oral mucosal melanin hyperpigmentation from single or multiple melanotic macules based on medical history and on clinical and histological grounds may be impossible as they share the same clinical and microscopical features and both may develop at a young age

Comer, Elizabeth Anderson (2003) Projects: National Institutes of Health, Bethesda, Maryland: Analysis and Interpretation of Aerial Imagery. Elizabeth Anderson Comer / Archaeology

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Yes, but use natural options like honey, stevia, or monk fruit to avoid counteracting its calorie-burning benefits