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Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance
These may include: Nausea, vomiting or diarrhoea (most common early on) Constipation Fatigue Mild increases in heart rate (similar to changes seen with GLP-1 medicines) Side effects were more frequent at higher doses (8 mg and 12 mg), but still rated mild to moderate overall
DOI Scopus119 WoS112 Europe PMC92 2014 Akison, L., Boden, M., Kennaway, D., Russell, D., & Robker, R
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