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Vitamin B12: Oral compared with parenteral
Parry Strong A, Haeusler S, Weatherall M, Krebs J (2016) Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomized trial

Visual inspection of the funnel plot (Figure 24) did not indicate substantial asymmetry

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And, when your system is stressed it can respond by producing too much (or too little) cortisol