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Alpha-lipoic acid is found in small amounts in foods such as spinach and broccoli and is also synthesised in the liver [125]

This relatively high concentration helps protect the stability of the red blood cell membrane and prevents hemoglobin from being oxidized to methemoglobin, thereby preserving its oxygen-carrying capacity

In Organic Electrochemistry , 5th ed

however, such high concentrations of H 2 O 2 are improbable under physiological conditions in vivo because H 2 O 2 is then degraded to oxygen and water by the reaction with catalase, peroxiredoxin (Prx), or GSH peroxidase (GPx) (Figure 1)

Primary increases within subregions of the scACC in depressed populations have also been reported in functional studies