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This gene is part of a family of genes, referred to as the HLA complex, that is strongly associated with common autoimmune diseases including type 1 diabetes, celiac disease, and multiple sclerosis (Kaukinen 2002
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In Vivo Study Taking into consideration the results from the series of screening studies above, Compound 1.70 was selected for in vivo study as it showed retention in activity with all of the key enzymes (GST, GPx, and GR) while also displaying improved stability, as opposed to the other compounds that had lost activity with one or more key enzymes
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10.1016/j.bbalip.2011.10.008
