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Overexpression of ALAS2 or supplementation of glycine (an ALA precursor), could not rescue heme synthesis in ABCB10-deficient cardiomyocytes, leading to their conclusion the only reason for the heme defect was that ABCB10 promotes export of ALA from the mitochondria
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If the B12 shot is painful, then your muscles impulsively flex as a reaction to the needles insertion
