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Collectively, these data indicated that gut microbiota directly, or through the production of SCFAs, can impact the gut hormone levels, thereby influencing health and disease outcomes

encapsulated entacapone into PEGylated PLGA (PEG-PLGA@Ent) nanoparticles and nanostructured lipid carriers (NLCs) to enhance its bioavailability and pharmacological efficacy while mitigating its limitations, such as low oral bioavailability and rapid clearance 130

Arterioscler Thromb Vasc Biol 27:943948 Schulz E, Jansen T, Wenzel P, Daiber A, Mnzel T (2008) Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension

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