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As a result of the use of alternative promoters and through alternative splicing there are four major isoforms of glutaminase enzymes

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Gut 66(6):11381153 Drod K et al (2021) Metabolic-associated fatty liver disease (MAFLD), diabetes, and cardiovascular disease: associations with fructose metabolism and gut microbiota

Both cytosolic and peroxisomal isoforms of Cu/Zn-SOD rely on zinc for stability and activity, and MTs serve as zinc buffers, releasing zinc under oxidative stress to fine-tune redox signaling and enzyme expression 94

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest