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doi: 10.1007/s11356-013-2281-x 78 AmaralARamalho-SantosJSt JohnJC
Consequently, reducing the population of pro-fibrotic M2 macrophages and shifting the macrophage balance toward an anti-fibrotic phenotype may offer a promising therapeutic approach
However, the complexity of human brain injury and the limitations of animal models in predicting human neurological outcomes require extensive clinical validation before considering these applications
