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Anyway, the fact that IGF-I redistribute among extravascular IGFBPs after passing the endothelium is likely to affect the local tissue bioavailability even more

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Proc Natl Acad Sci USA 100:1140611411 [DOI] [PMC free article] [PubMed] [Google Scholar] Bagley EE, Chieng BC, Christie MJ, Connor M

The lipid-based delivery system also supports better utilization in those with compromised digestive function, which is common in older adults

Long-term improvements in gut health are more often tied to consistent nutrition habits, like eating patterns that support digestion, getting a range of nutrients, and maintaining balance without unnecessary restriction