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Acknowledgements The authors are grateful to the research assistants of Biology Department of Arak University and also the members of Roya Infertility Center in Qom for their support and cooperation throughout this research

The condition frequently worsens during summer months and often requires ongoing maintenance to prevent recurrence

A landmark paper on the clinical and immunological basis of the disease that is the essential paradigm of B12 deficiency and its immunological basis

doi: 10.3389/fimmu.2021.714833 189 LiuBFreeDNA