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The first of these, a PROteolysis TArgeting Chimera, or PROTAC, was published by Sakamoto et al
Table 1 summarizes data from preclinical studies
You will feel relaxed, experience altered mood, feel a little warmer, and may make poor judgments
Inevitably, even minor alterations in FcRn binding properties of a protein fusion can therefore affect the ability of the receptor to rescue it from intracellular lysosomal degradation
Biochemistry 2004, 43 (39), 1258512591
