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Gld/gld mice, characterized by a mutation in the FasL gene leads to a non-functional FasL molecule, also develop lymphoproliferation, hypergammaglobulinaemia and immunoglobulin deposits in the kidneys [99]

Another compound derived from sCR1, the APT070, also known as Mirococept was tested in preservation solutions (14, 72)

Many of these studies rely on the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Human Pancreas Analysis Program for Type 2 Diabetes (HPAP-type 2 diabetes) repository or the consolidated PanKbase ( [43]

Here, we describe a senolytic screen using a library of electrophilic compounds

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